MPH^® Technology

MPH^® (Microporous Polysaccharide Hemospheres) represents a new process for effecting almost instantaneous hemostasis at wound sites, even in the presence of profuse bleeding. The technology consists of an engineered biopolymer, microporous particle, with a controlled pore size, which is designed to act as a sieve to dehydrate the blood and thus serve to accelerate the natural blood clotting process. Applied topically, MPH^® gels rapidly with no tissue irritation, creating a protected environment for hemostasis and healing. The particles, or “beads,” are derived from plant-based biomaterials with an extensive history of use in humans. The final packaged material is stable, bio-inert and sterile. Following is a summary of the benefits of the technology.

Click here to see a short animation illustrating the Mode of Action of MPH^®

MPH^®: Features and Benefits

• Bio-inert — no inherent risk of disease transmission
• Contains no human or animal proteins — hypoallergenic
• Effective even in areas of profuse bleeding
• Stable base materials with extended shelf life
• User-friendly, one-step application with no mixing
• Rapid time to wound hemostasis as shown in initial animal studies
• Multiple cost reduction benefits for patient and provider

MPH^® Mode of Action:
Arista^®AH has been shown to safely and effectively accelerate the intrinsic blood clotting cascade with no inherent risk of adverse events.

When applied directly to an actively bleeding wound, each Arista^®AH particle acts as a molecular sieve to instantly extract fluids from blood.

This powerful osmotic action causes the particle to swell and concentrates serum proteins, platelets and other formed elements on its surface.

The hemostatic particles and their coating of compacted cells create a scaffolding for the formation of a tenacious fibrin clot within just minutes of application.

The Arista^®AH hemostatic particles are fully absorbed and enzymatically cleared from the wound site within 24 to 48 hours.